Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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At the end of the experimental period, the clinical symptoms were more pronounced. Supplemental naringenin adztringens intestinal barrier defects and inflammation in colitic mice. There are sepals on the flower all ranging from 1. Open in a separate window. A Disease Activity Index score was used as a reliable tool to assess the extent of the gastrointestinal disease in the DSS-induced experimental colitis.

Quercetin was used as a reference positive control. Recent studies have shown that the active component responsible for the plant properties is the anacardic acid [ 19 ] which exerts antioxidant, anti-inflammatory [ 20 ], antitumoral [ 21 ], antiulcer and antimicrobial activities [ 919 ]. The activity of antioxidant enzymes in colonic tissues of control and experimental group of mice is shown in Figure 4.

Evidence-Based Complementary and Alternative Medicine

The model used in this work to evaluate the antiproliferative activity was the assay with Sulforhodamine B an anionic dye that allowed the evaluation of antitumor activity through exposure of selected human tumor cell lines during exponential growth phase, at different concentrations of the A. With respect to the antioxidant capacity, generally, phenolic compounds are zdstringens for biological activities as antioxidant capacity and inhibition of enzymes involved in common diseases.

EGCG reduces experimental colon injury by inhibiting macrophage chemotaxis toward N-formyl-L-leucyl-L-phenylalanine, thereby suppressing the mast cells and macrophage activities [ 43 ].

Subscribe to Table of Contents Alerts. Mice were sacrificed using CO 2 amphiptwrygium, and all efforts were made to minimize pain. Trees and Shrubs of Mexico pt. This plant usually blooms in the summer, from June to August, and tends to fructify produce fruits from August to January.


Digestive Diseases and Sciences. Additionally our results provide novel evidence that A. These phytochemicals compounds of AaEE have been found to induce a wide amphiterygium of activities such as reduction in oxidative stress, suppression of inflammation, and cell proliferation and modulating numerous amphiterygium transduction pathways.

Our results provide evidence of potential antifungal application of A. Rt min Name Type 3. The pharmacological activity of medicinal plants appeared to correlate with the presence of active compounds having antioxidant and adstrinfens activities.

Biochemical and Biophysical Research Communications. The presence of hydroxyl groups in the structure also enhances the inhibition of lipid peroxidation [ 4041 ].

Amphipterygium adstringens – Useful Tropical Plants

Naringenin is another important flavonoids present in AaEE. Competing Interests The authors declare that there are no competing interests. Published online Aug Therefore, our findings indicate that AaEE treatment of colitis might be reducing the extent of colonic injury by its antioxidant ability.

Experimental colitis models have been used to identify therapeutic agents and elucidate the underlying physiologic mechanisms of UC.

MIC was determined as the lowest concentration of CE that inhibited microorganism growth. Results were expressed as SC 50 Table 1. Chlorhexidine is the most common mouthwash product used for caries and periodontal diseases and kills bacteria by causing a precipitation or coagulation of the cytoplasmic content. Protective effect xmphipterygium Calculus Bovis Sativus on dextran sulphate sodium-induced ulcerative colitis in mice.

Abstract Amphipterygium adstringens is a plant widely used amphipterygihm Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Moreover, anti-inflammatory, hypocholesterolemic, antifungal, and antiprotozoal activities have also been reported as properties for this plant [ 10 — 19 ].

In this regard, the use of alternative therapies zdstringens emerged as a common approach in gastrointestinal diseases; actually, studies describe that almost half of IBD patients have ever taken or currently use complementary remedies [ 56 ]. The formaldehyde produced is measured colorimetrically with 4-aminohydrazinomercapto-1,2,4-triazole Purpald as the chromogen.


Amphipterygium adstringens Scientific classification Kingdom: Our observations are in agreement with those reported in other studies using the DSS-induced colitis model [ 226 ].

These effective antimicrobial and antiproliferative activities make A. Additionally, the constantly observed correlation between oral microbiome especially biofilm builders [ 28 ] with chronic inflammatory disease and cancer triggers the need for further research that contributes with novel sources of bioactive compounds.

After filtration, the solvent was evaporated under reduced pressure, generating the ethanol extract AaEE. Microbial communities in the mouth have been shown to cause infectious diseases such amphipterhgium dental caries [ 23 ], candidiasis [ 24 ], gingivitis and periodontitis amphiprerygium 25 ], and other chronic or systemic diseases [ 26 — 28 ].

There exists an increasing prevalence of infections worldwide, due to, among other reasons, the growing resistance of pathogens to antibiotics and antifungals as well as alterations in the autoimmune system. Cytokine ampjipterygium in inflammatory bowel diseases. The method is based on the reaction of the enzyme with methanol in the presence of an optimal concentration of H 2 O 2. In addition, we found that the colon was significantly shorter in the Adsgringens mice The widely employed DSS-induced colitis model recapitulates the histological characteristics of UC [ 89 ].

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

Similar results are exhibited by A. The mortality in the Adstrintens group started at day 13, According to Al-Fatimi et al. Alimentary Pharmacology and Therapeutics. We investigated the effects of alcoholic extract of A. Streptococcus mutans is the main pathogenic agent related to the initiation of dental caries.

However, further research should be made to test whether secondary metabolites from A. De La Rosa, and G. Protective adstrinbens of Laminaria japonica with probiotics on murine colitis.