Malar J. Nov 26;17(1) doi: /sy. Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high. Aspidosperma pyrifolium Has Anti-Inflammatory Properties: An Experimental Study in Mice with Peritonitis Induced by Tityus serrulatus Venom or Carrageenan. Find technical and marketing information for lesser-used tropical timber species, LUS. Learn more on our Jitichuriqui (Aspidosperma pyrifolium) page.

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Toxicity towards human hepatoma cells, monkey kidney cells or human monocytes freshly isolated from peripheral blood was also assessed.

Published online Oct Steps 17 – Tree Conservation Database. Common Names Jitichuriqui Bolivia. The analysis shows one peak retention time: The Apocynaceae family has considerable economic and medicinal importance [ 1718 ].

The envenomation induced by scorpions of the genus Tityus spp.

Jitichuriqui (Aspidosperma pyrifolium) | ITTO

In this study, the effect of A. Further assays should be done to verify if the extract may present cytotoxic activity against tumor cells, as observed in Himatanthus drasticusa medicinal plant from the same family, of which the uses in traditional medicine are supported by reports of its uses in cancer treatment, as an anti-inflammatory medication, and to stimulate the immune system [ 32 ].

Recent studies by our group have demonstrated the beneficial effect of the use of plant extracts in the local treatment of snakebite [ 13 ], but there are few studies exhibiting the effectiveness of such treatment in envenomation induced by scorpion sting [ 10141516 ].

Find articles by Hugo Alexandre Oliveira Rocha. Edema and vascular ectasia were observed in the lung tissues of envenomed mice Figure 6 B. Envenomation by scorpion of genus Tityus spp. The analyses of AE A. Acknowledgments The authors acknowledge all participants for their valuable time and commitment to the study. This model is a well-characterized experimental model aslidosperma acute inflammation, largely employed to evaluate new anti-inflammatory therapies focusing on quantify or analyze peritoneal vascular permeability and cellular migration as well as changes in other inflammatory parameters [ 33343536 ].


Compounds 67 and 8 correspond to chlorogenic acid isomers, n -chlogenic, crypto-chlorogenic and iso-chlorogenic acid, respectively. Rays more than 10 per mm abundant.

Insulin-like effects of Bauhinia forficata aqueous extract upon Tityus serrulatus scorpion envenoming. Envenomation was first induced in various doses to verify the dose, which could cause an increased inflammation without promoting death of the animals.

The carrageenan-induced peritonitis resulted pyrifolijm an increase in total number of cells that migrated into the peritoneal cavity, and was observed the anti-inflammatory effect of aqueous extracts of A.

Clinical consequences of Tityus bahiensis and Tityus serrulatus scorpion stings in the region of Campinas, southeastern Brazil. De Souza Lima Aspifosperma. The peritoneal cell infiltration was analyzed after 6 h. Biological and cytotoxic effects. A comparative study of the cellular, exudative and histological responses to carrageenan, dextran and zymosan in the mouse. On Asclepiadoideae plants, which are a subfamily of Apocynaceae, phytochemical studies verified the presence of phenolic compounds, as well as the flavonoids quercetin, rutin and isorhamnetin [ 2122 ].

The separation was performed using a Reverse Phase Luna C column 4. The presence of rutin was confirmed by comparison with reference standard data.


Support Center Zspidosperma Center. To verify the time with the highest cell migration for subsequent assays, the animals received an i. This is the first study pyrifolimu on the ability of rutin and aqueous extracts of A. In conclusion, this approach demonstrated that aqueous extracts of A.

The cell viability of the 3T3 cells was analyzed after 48 and 72 aspidopserma of incubation with aqueous extract of A. Aspidosperma pyrifolium activity was evaluated against Plasmodium falciparum using extracts in vitro. Histopathology Analysis Edema and vascular ectasia were observed in the lung tissues of envenomed mice Figure 6 B.

These results exhibited the anti-inflammatory action of the aqueous extract of A. The experiment was performed in triplicate. Color The sapwood is differentiated, it is light brown, the heartwood is reddish brown.

Euphorbiaceae inhibits enzymatic and biological actions of Bothrops jararaca snake venom. All solutions prepared for HPLC analysis were filtered through a 0.

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Table 1 summarizes the anti-inflammatory activity of aqueous extract and rutin in carrageenan-induced peritonitis model.

When compared with the saline group Figure 6 Athe lung tissues of envenomed mice presented a dense inflammation in the perivascular and peribronchiolar areas, and thickened interstitial space alveoli walls due to intense inflammation. National Center for As;idosperma InformationU. Basic Density or Specific Gravity O.