BIOASSAY OF INSULIN BIOASSAY OF D-TUBOCURARINE MERITS OF BIOASSAY DEMERITS OF BIOASSAY REFRENCES. is being done through. Bioassay, official method, adrenaline, digitalis, d-tubocurarine, heparin, insulin, oxytocin, gonadotropin, chorionic gonadotropin, urokinase, streptokinase. Second 4 x 4 latin square bioassay was performed using a series: with a The presence of d-tubocurarine was demonstrated in the Peruvian.

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The potency of test sample is calculated from the standard curve. In order to view d-fubocurarine, please contact the author of the presentation.

Those rabbits which received the standard sample on the first day will be given test sample on the second day of expt. First group will receive standard sample and the second group will receive the sample under test.

PHARMACOLOGY: Bioassay of D-Tubocurarine

Newer Post Older Post Home. Presentation D-tubocuearine No description available. Minimum 8 rabbits are used. Automatically changes to Flash or non-Flash embed. Saturday, 12 May Bioassay of D-Tubocurarine. It is a perfect in vitro model. Bioassay of D- Tubocurarine. Jyotirmoy Das Choudhury M.

Helps to flexing lumbar spine. You do not have the permission to view this presentation. Acetylcholine contraction is recorded on slow moving drum for 90 sec. Receptors The rectus abdominis muscle of frog mainly rich of Nicotinic receptor.


Have a nice day. Rabbits recover immediately from the effect of curarization. Blood supply to Rectus muscle. Rabbits weighing 2 kg. Share to Twitter Share to Facebook. Bioassay of D-Tubocurarine 1.

Screening Methods In Pharmacology. It is also useful for bioassay of Acetylcholine. Receptors present in Rectus muscle. They mainly respond to the acetyicholine released from motor neuron terminal. Conclusion Rectus abdominis muscle of frog has various importance in pharmacology.

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Ringer Solution 11 Components Amount gm Nacl 6. The presentation is successfully added In Your Favorites. God Bless you man. Rabbit head drop method for the bioassay of d-tubocurarine.


The percentage reduction at each dose levels is calculated and log dose response curve of the standard drug is plotted. College of Pharmacy, Ahmedabad. WordPress Embed Customize Embed.

I enjoy, result in I found exactly what I used to be looking for. Location d-tubofurarine Rectus muscle. Pharm 1 st semester Phamacology Under the Guidance of Mr. The responses are recorded using isotonic frontal writing lever with 1 G.

Cross-over test is carried out to minimise biological error due to animal variation. Functions It is an important postural muscle. Numerous small segmental contribution coming from lower inter costal arteries.

Infusion is continued till the rabbit will not be in a position to hold its head erect or there will be no response by focussing light on the eyes and the neck gets elongated and toneless. Animals should be free from disease, obtained from a healthy colony and should be accustomed with vioassay experimental procedure.


Mean dose which produces head drop of the test sample is compared with the mean dose of standard preparation. They are divided d-tubovurarine two groups each containing 4 rabbits. The total amount of og sample required to produce the endpoint is compared with the total amount of the standard sample required to produce similar endpoint.

Upload from Desktop Single File Upload. Head drop after injection. The head should be freely movable. Two similar contractions with the same concentration of acetylcholine are obtained. Location The rectus abdominis is a long flat muscle, which extends along the whole length of the front of the abdomen. Plays an important hioassay in breathing It helps to keep internal organ intact. Go to Application Have a question?

Injection should be given at a rate of 0. Rectus abdominis muscle is a paired muscle running vertically on each side of the anterior wall.

Suitable dose of d-tubocurarine is 0.