Common Name: West African Rubber Tree. Funtumia elastica. Drawing of the leaves and flowers. Photograph by: Matilda Smith Public domain. Funtumia elastica (Preuss) Stapf [family APOCYNACEAE]. Common names. English West African rubber tree; Lagos silk rubber tree; bush rubber (Ghana. Description. Tree to 30 m tall; bole straight and cylindrical, crown narrow; bark brown to dark, thin, slightly fissured, becoming granular on old trees; Slash orange.

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Error bars represent SD. Anim Health Res Rev.

Funtumia elastica

After 5 days, the cells were analyzed by two-color flow cytometry. National Center for Biotechnology InformationU. In Africa some parts of the tree are also used medicinally: Views Read View source View history. Author manuscript; available in PMC Oct 1.

Depletion of a gamma delta T cell subset can increase host resistance to a bacterial infection. Innate immunity for biodefense: GraffEmily M. Therapeutic treatment with Yam-I resulted in decreased bacterial counts in feces from mice with Salmonella enterica serotype Typhimurium ST -induced enterocolitis. Cookies help us deliver our services.

Approximate molecular weights were determined funtumla calibration with pullulan standards as follows: Representative of at least 3 experiments. These fractions were analyzed by HPLC, and elution was monitored with a refractive index detector as described previously [ 30 ]. Isolation, characterization and antiplasmodial activity of steroidal alkaloids from Funtumia elastica Preuss Stapf.

Asthma is considered a T H 2 cell-mediated disease, and treatments that increase T H 1 responses can be effective in alleviating symptoms [ 54 ]. Fractionation and characterization of biologically-active polysaccharides from Artemisia tripartita. Bradley Jones, University of Iowa for use in an enterocolitis model of ST infection involving pretreatment with streptomycin [ 33 ]. The majority of in vitro macrophage activation exhibited by extracts of some immune enhancing botanicals is due to bacterial lipoproteins and lipopolysaccharides.


The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Flowers in axillary, many-flowered cymes, 5-merous, white to yellowish; peduncle 1 cm long; pedicel mm long; calyx 5 mm funtumis, deeply divided, segments on the inside with 2 glands; corolla salver-shaped, tube mm long, segments oblong, about 5 mm long.

Cells were plated 2. HeJ mice were treated with the 3 sub-fractions of Yam-I in a priming assay, and proliferation was measured using CFSE staining in flow cytometry. KimmelBrett FreedmanIgor A. Eight hours after infection, mice were treated with varying doses of Yam-I by i. Lines in Figure 2 represent the average relative gene expression levels of genes that changed at least 1. Thin bar indicates dlastica, thick error bars represent SEM.

Thus, related polysaccharides of various sizes comprise the Yam-I fraction. Twenty-four hours after infection, mice were euthanized and fecal pellets were collected. Clearly, Yam-I functionally overlaps with LPS to some extent but the intestinal mucosa is constantly exposed to LPS from food, environment and normal flora. Negative regulation of airway responsiveness that is dependent on gamma delta T cells and independent of alphabeta T cells.


Dittmer U, Olbrich AR. Seven hours post-infection, mice were treated by i.

Inhibition of murine neutrophil recruitment in vivo by CXC chemokine receptor antagonists. As a service to our customers we are providing this early version of the manuscript.

Antimicrobial and anti-inflammatory properties of Funtumia elastica.

By using our services, you agree to our use of cookies. Slight differences were detected between the 3 sub-fractions.

Seed fusiform, about 1. West Indian Med J. HeOuJ mice 5 mice per groupand peritonitis was similarly measured.

Funtumia elastica – Useful Tropical Plants

Jutilaand Jodi F. This is a PDF file of an unedited manuscript that has been accepted for publication. The bark contains a white latex which coagulates readily and produces about one-third of its weight of pure rubber. Yam-I obtained from before and after two sequential rounds of PMB treatment was tested in the peritonitis model using C3H: Therapeutic treatment with Yam-I provided increased innate protection from mucosal infection with Salmonella enterica serotype Typhimurium ST.

Discussion Both prophylactic and post-exposure strategies involving innate immune stimulation by adjuvants have been shown to prevent or ameliorate infections [ 4445 ].

Suppression of allergic reaction by lambda-carrageenan: At present it is economically of no importance. J Agric Food Chem.