The relationship between sleep apnea syndrome and hypothyroidism

The relationship between sleep apnea syndrome and hypothyroidism.

the relationship between sleep apnea syndrome and hypothyroidism

Thus this study did not reveal any relationship between OSAS and thyroid disease. On the other hand, the suspect of sleep apnea in hypothyroid patients, . Feb 8, discusses the relationship between hypothyroidism and sleep Orr and Martin, ) The prevalence of OSA syndrome (AHI> 5/hour and. Chest. Dec;(6) The relationship between sleep apnea syndrome and hypothyroidism. Lin CC(1), Tsan KW, Chen PJ. Author information.

The current study, however, contains some limitations. Thyroid function tests were performed only once, which may have increased false positivity in current study subjects since the nocturnal peak of serum TSH may be delayed in those with irregular sleep patterns [ 32 ].

the relationship between sleep apnea syndrome and hypothyroidism

However, the strength of this study was the large number of investigated subjects, allowing for the analysis of detecting small effects and the quite strict inclusion and exclusion criteria used. Moreover, characteristics of the study design, cross-sectional one, did not allow us to draw a causal relationship between OSA and increased serum TSH. Increased serum TSH is associated with some of the cardiometabolic risk factors and the small TSH changes, if chronic, may contribute to the development of disease conditions [ 713 ], and thus performing thyroid function testing in hypertensives with OSA is reasonable.

Competing Interests All the authors who participated have nothing to disclose and have no conflict of interests to report.

The relationship between sleep apnea syndrome and hypothyroidism.

Acknowledgments The authors would like to thank both the subjects of study for participating in the present research and the staff of Diagnosis, Treatment and Research of Hypertension in Xinjiang.

Foschino Barbaro, and G. Subsequently, he was referred to our sleep clinic for ruling out SDB. His family reported snoring of moderate severity for several years, but no witnessed apneas or nocturnal arousals with respiratory difficulty.

He had mild excessive daytime sleepiness EDS quantified by Epworth sleepiness scale of He had no vascular risk factors or history of substance abuse.

the relationship between sleep apnea syndrome and hypothyroidism

Examination showed a moderately built individual with BMI His cardiac evaluation was normal. His thyroid profile showed hypothyroidism thyroid-stimulating hormone 30 normal 1—5 unit with low free T3 and free T4.

Considering the possibility of untreated hypothyroidism presenting as SDB, we initiated him on L-thyroxine replacement at a dose of 0.

The relationship between sleep apnea syndrome and hypothyroidism. - Semantic Scholar

Polysomnography showing multiple central sleep apneas with arousals Click here to view At 3 months, he denied any EDS Epworth sleepiness scale 8 only and was feeling more energetic at workplace.

He had been found to have primary hypothyroidism TSH He had a history of non-Hodgkin lymphoma, treated 4 years earlier with chemotherapy and mantle radiation, in remission; prior thyroid function studies were not available. Medications included cetirizine, fexofenadine, and alprazolam; the last medication had been started due to difficulty sleeping.

Physical examination revealed an obese Caucasian male BMI Vital signs were remarkable for tachycardia heart rate Examination was unremarkable except for obesity, large neck circumference 19 inchesand agitated, belligerent behavior.

  • The relationship between sleep apnea syndrome and hypothyroidism.
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Laboratory studies demonstrated elevated TSH Serum toxicology screen revealed no alcohol or illicit substances. He was admitted to the critical care unit; because of severe agitation, he received intravenous sedation.

the relationship between sleep apnea syndrome and hypothyroidism

Because of possible rhabdomyolysis presumably due to agitation and muscle traumahe received intravenous hydration with sodium bicarbonate. After 72 h, his symptoms had improved markedly, and serum creatine kinase returned to normal after several days.

Given his obesity, poor sleep quality, and snoring, a polysomnogram was ordered at that time; this was performed and revealed an apnea-hypopnea index AHI of